Prodrug based on polymers are pictured macromolecules and these prodrugs performance unique angle to raise the solubility and pharmacokinetics and pharmacological properties. According to their benefits as anticancer drugs, the highlights focused on the synthesis of prodrug polymers and their applications in medicine field, So these polymers having degradable amide bonds linked to paracetamol and ester bonds bounded to ciprofloxacin as a material for drug delivery . The characterization of the r