The fatty acid composition of Pinna nobilis samples collected from Phan Rang Bay and South Binh Thuan, Vietnam, was investigated. A total of 40 fatty acids, with chain lengths ranging from C14 to C24, were identified across the samples. The fatty acid profiles exhibited notable diversity, comprising saturated fatty acids (SFAs), branched-chain saturated fatty acids, monounsaturated fatty acids (MUFAs), and polyunsaturated fatty acids (PUFAs). SFAs accounted for 39.09% of the total fatty acids in