Machine learning and radiomics for differentiating severe from moderately severe acute necrotizing pancreatitis on contrast-enhanced computed tomography

BACKGROUND Acute necrotizing pancreatitis (ANP), a more severe form of acute pancreatitis, requires early diagnosis and accurate severity stratification for optimal patient prognosis and treatment. Currently, most scholars do not clearly differentiate between ANP and severe acute pancreatitis, although they are distinct clinical entities. AIM To investigate the value of radiomics derived from contrast-enhanced computed tomography (CECT) of the pancreatic parenchyma and peripancreatic necrotic co