Liver transplantation (LT) is a complex surgical procedure often accompanied by massive intraoperative blood loss, necessitating transfusion of blood and blood products. However, transfusion of allogeneic blood has been consistently associated with adverse outcomes, including increased post-transplant morbidity and mortality, higher rates of infection, acute kidney injury, and reduced graft survival. Allogeneic blood transfusion also exerts immunomodulatory effects that may influence both short-