The persistence of fluoroquinolone antibiotics like ofloxacin (OFL) in aquatic systems leads to emergence of antimicrobial resistance (AMR) and need better technology to monitor its effects on the environment/health. The implementation of real-time and decentralized monitoring systems remains constrained due to their dependency on slow and resource-intensive technique. To overcome these challenges, an electrochemical platform based on ternary nanocomposites of reduced graphene oxide-copper-gold