Objectives The objective of this study was to analyze the relation of patient health questionnaire (PHQ-9) scores with the extent of COVID-associated mucormycosis (CAM), the surgical approach used for treatment, the extent of surgery (structures removed), and to report the epidemiology of CAM in Eastern India, where the incidence of mucormycosis is rare. Material and Methods This is a cohort study done from May 2021 to July 2021, which was performed at a tertiary care institute in Eastern India.