iScience

Frontal lobe integrity is crucial for risky decision-making. We investigated how frontal lesions affect computational mechanisms underlying risk when decisions impact oneself versus others. Twenty patients with frontal damage and 20 matched controls accepted or rejected mixed-outcome gambles for themselves or an anonymous other. Patients accepted more disadvantageous gambles than controls in the …

This backstory is based on an interview with Prof. Pengxin Liu by a student group from ShanghaiTech residential college. The original intention of the interview was to introduce the other identity of Prof. Liu, as a science influencer on social media with over 1.6 M followers, to the undergraduates. Here in this backstory, we share our conversation on the motivation, skill, and outcome for engagi…

Neurological disorders are often associated with neuronal dysfunction. Neuroblastoma (NB) cell line SH-SY5Y is widely used as in vitro model as it can differentiate into neuron-like cells. Many other NB cell lines can also respond to differentiation treatment but their potential in neuronal modeling remained unexplored. We evaluated 18 NB cell lines using RNA-seq and differentiation treatment wit…