Trichotillomania (TTM) and skin-picking disorder (SPD) are body-focused repetitive behavior disorders (BFRBDs) associated with deficits in emotion regulation, distress tolerance, and experiential avoidance. Their differential relations to TTM, SPD, and their comorbidity, and relative importance in predicting BFRBD outcomes is unclear. Therefore, this study compared these constructs in adults (n = 311) diagnosed with TTM (n = 112), SPD (n = 87), comorbid TTM and SPD (n = 40), and healthy controls