Synthesis and biological studies of some novel furo naphthyridine compounds contain chalcone

Through a Vilsmeier–Haack condensation 2-chloro-3-formyl-1.8-nathyridine (I) was synthesized. When treated with aqueous hydrochloric acid converted to compound (II) was successfully obtained in high yield and then converted to Novel 1-(8-methyl) furo[2,3-b] -(1,8-naphthyridine-2-yl) ethenone (III) through Claisen –Schmidt condensation. The condensation between compound III (ketone) and benzaldehyde yield Novel (furo[2,3-b] (1,8-naphthyridine-2-yl)-2- acetyl called chalcone (4). The reaction betw