X-linked Severe Combined Immunodeficiency Syndrome with Hereditary Spherocytosis in an Infant: A Rare Case Report

Combined Immunodeficiency is an uncommon and inherited Primary Immunodeficiency Disorder (PID) that affects both cellular and humoural immune function and leads to early death. This case report describes the rare co-existence of X-linked Severe Combined Immunodeficiency (SCID) and Hereditary Spherocytosis (HS), highlighting new mutations, challenges in diagnosis and managing complex paediatric cases. A five-month-old male infant, born through vaginal delivery, presented with persistent fever, re