La radiologia medica

Abstract Purpose To investigate body composition as a predictive biomarker of cancer-related death in patients with non-metastatic colon cancer (CRC). Materials and methods Patients with CRC (stages II–III) treated with upfront surgery, with availability of baseline CT, clinico-histological and survival data were retrospectively enrolled. Patients with stage IV or CT unavailability were excluded.…

Abstract Objectives To evaluate whether baseline splenic ^18F-FDG PET uptake and CT-derived spleen volume predict early progression (≤ 36 months) and progression-free survival (PFS) in diffuse large B cell lymphoma (DLBCL), and whether they interact. Materials and methods Retrospective cohort of adults with newly diagnosed DLBCL undergoing baseline ^18F-FDG PET/CT and CT. Splenic PET positivity w…

Abstract Background This study aimed to evaluate clinical outcomes in patients with vaginal recurrences treated with radiotherapy with or without chemotherapy, followed by image-guided interventional radiotherapy (IG-IRT). Methods We retrospectively analyzed patients with vaginal recurrences treated with external beam radiotherapy (EBRT) ± chemotherapy followed by endovaginal high dose rate IG-IR…

MRI NI-RADS showed moderate inter-rater agreement in OPSCC patients, with greater interpretative challenges in the evaluation of the first post-treatment MRI. Regular application of the NI-RADS in clinical settings may help enhance consistency and reliability in imaging evaluations.

CT-guided SIJ injection is a safe and effective intervention for sacroiliitis, yielding sustained pain relief and functional improvement across both inflammatory and degenerative etiologies, independent of age and BMI.

To enhance the quality of organized mammographic screening in Italy, in accordance with national legislation, a multidisciplinary panel of experts applied the Grading of Recommendations, Assessment, Development and Evaluation (GRADE)-ADOLOPMENT approach to adopt or adapt the European Commission Initiative on Breast Cancer (ECIBC) guidelines concerning the use of digital breast tomosynthesis (DBT)…

Environmental exposures-such as airborne pollutants, metals, and urban stressors-contribute to cancer development and progression, yet their downstream biological effects remain difficult to characterize in vivo. Quantitative medical imaging may help fill this gap. Radiomics, in particular, offers access to tissue-level patterns shaped by chronic injury and microenvironmental remodeling. In this …

Low- and ultra-low-dose lung CT protocols represent an important advancement in cystic fibrosis imaging, providing sufficient detail to evaluate disease status while substantially reducing cumulative radiation exposure. By enabling reliable short-term assessment of CFTR modulator efficacy through established disease scoring systems, these protocols fill a critical gap in the routine follow-up of …

The findings provide preliminary evidence of cerebellar GM changes in patients requiring hip prostheses, suggesting central nervous system involvement in chronic hip pathology. Interpretation is constrained by the modest sample size and by variability in postoperative imaging intervals. The absence of significant postoperative changes highlights the need for further research to explore the timeli…