Asian Journal of Medical and Pharmaceutical Sciences

Paper
Muneendra Madam·...·Manjula Chella
2d ago

Artificial intelligence (AI) has transformed the drug discovery process, dramatically speeding up the identification of potential drug targets, the optimization of drug candidates, and the movement of compounds from the laboratory to the clinic. With the use of AI technologies, notably deep learning and machine learning methodologies, researchers have been able to analyze large datasets, find hid…

Computational Drug Discovery Methods

An ancient disease, its bacterial agent (Yersinia pestis) still causes periodic outbreaks and remains endemic in some parts of the world. Additionally, because it could be weaponized for world bioterrorism, understanding its clinical syndromes, epidemiology, and treatment options remains critical for medical practitioners. Finally, recent molecular discoveries linking recessive familial Mediterra…

Biochemistry, Genetics and Molecular BiologyGeneticsLife SciencesYersinia bacterium, plague, ectoparasites research

The emergence of antimicrobial resistance has intensified the need for alternative therapeutic strategies, particularly plant-based combinations exhibiting synergistic effects. The present study investigates the antibacterial potential of ethanolic leaf extracts of Moringa oleifera and Hibiscus rosa-sinensis, individually and in combination. Extracts were prepared by maceration and evaluated for …

Agricultural and Biological SciencesLife SciencesMoringa oleifera research and applicationsPlant Science

The present study was designed to evaluate the anti-inflammatory and immunomodulatory potential of the ethanolic extract of Cucumis sativus peel (EECS) using in vitro and in vivo experimental models. The extract was obtained as a greenish-brown solid with a percentage yield of 21.5%. Preliminary phytochemical screening revealed the presence of alkaloids, flavonoids, terpenoids, tannins, saponins,…

Advances in Cucurbitaceae ResearchBiochemistry, Genetics and Molecular BiologyGeneticsLife Sciences