pediatrics

BackgroundChildren with solid tumors experience prolonged treatment, repeated hospital visits, and psychosocial stressors. This exploratory single-center cross-sectional study evaluated anxiety symptoms, depressive symptoms, and health-related quality of life in children with solid tumors and examined their associations with selected sociodemographic, clinical, school functioning, and social func…

Brief videos shown in the hospital newborn nursery may be an effective way to educate first-time fathers on infant care topics, such as safe sleep, infant crying and car safety, according to a pilot study published in the journal Pediatrics Open Science.

IntroductionDigital therapeutics (DTx) for children with ADHD have gained attention as adjunctive interventions to pharmacotherapy; however, evidence remains limited regarding the mechanisms underlying training performance decline and the clinical effectiveness of performance data–driven personalized protocols. This study aimed to identify the core mechanisms of performance decline using digital …

Brief videos shown in the hospital newborn nursery may be an effective way to educate first-time fathers on infant care topics, such as safe sleep, infant crying and car safety, according to a pilot study published in the journal Pediatrics Open Science.

BackgroundThis study provides the first long-term efficacy and safety data of selumetinib in Chinese pediatric patients with inoperable symptomatic plexiform neurofibromas (PN) associated with neurofibromatosis type 1 (NF1).MethodsIn this single-center Phase I clinical trial(NCT04590235), we enrolled children with NF1-related PN aged 3 to <18 years and treated them with selumetinib at a dose of 2…

ObjectiveCommercial Chinese polyherbal preparations (CCPPs) are increasingly used for infantile anorexia (IA), but comparative effectiveness and safety differences among them remain unclear. This Bayesian network meta-analysis compares various CCPPs for IA to inform clinical practice.MethodsWe systematically searched CNKI, Wanfang, VIP, China Biology Medicine, PubMed, Web of Science, Embase, and …

It's a mystery. The eye disease known as retinopathy of prematurity (ROP) can make infants permanently blind if they are not treated. But there are big differences between how often Norwegian hospitals actually provide this treatment.

Metabolic and bariatric surgery for teens with severe obesity was found to be cost-effective over 10 years, according to the new analysis from Ann & Robert H. Lurie Children's Hospital of Chicago published in JAMA Network Open.

BackgroundCyproheptadine hydrochloride (CH) possesses both antihistaminic and appetite-stimulating properties, suggesting therapeutic potential for children with failure to thrive (FTT) and food allergies. This study evaluated the effects of CH on growth parameters, clinical manifestations, and serum levels of appetite-regulating peptides Nesfatin-1 and NUCB2 in children aged 1–3 years with FTT a…

Posted on: 15 June 2026, source: news-medical.net An eight-month-old baby from Israel has become the first human ever to receive an experimental gene therapy designed to replace a missing gene responsible for a devastating neurological disease that until now offered no hope of survival. The treatment was performed at Clalit-Schneider Children’s Medical Center, part of Clalit Health Services, Isra…

Some subgroups of children with precocious puberty-such as older girls with slowly progressing puberty-may not need the same level of testing or treatment, according to a new Endocrine Society Clinical Practice Guideline released today.

Some subgroups of children with precocious puberty--such as older girls with slowly progressing puberty--may not need the same level of testing or treatment, according to a new Endocrine Society Clinical Practice Guideline released today.

A $4 million grant from the National Institutes of Health (NIH) will help a UC Davis research team develop a lab-engineered graft to improve bladder reconstruction for children.

A joint study by the University of Oulu and Oulu University Hospital suggests that a newborn's upper lip frenulum is unlikely to be a major cause of breastfeeding difficulties.

Low concentration atropine eye drops are a safe and effective treatment for short-sightedness (myopia) in UK children, although the effects are small, suggests a clinical trial published by The BMJ today.

Boston Children's Hospital has been awarded up to $17.25 million to serve as a participating site within the Innovative Medicine and Precision Approaches to Clinical Trials (IMPACT) Network, an international effort funded through Aligning Research to Impact Autism (ARIA).

Dr. Jimmy Holder, associate professor in pediatrics at Baylor College of Medicine and Principal investigator at the Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital, and his team have received a grant for up to $17.25 million from Aligning Research to Impact Autism (ARIA) to become a part of the Innovative Medicine and Precision Approaches to Clinical Trials (IMPACT…

IntroductionIn recent years, telerehabilitation has been increasingly used to improve access to care for children and adolescents with intellectual disability (ID). However, the available evidence is still limited and highly heterogeneous. This systematic review aimed to evaluate the impact of telerehabilitation interventions on cognitive, behavioural, and functional outcomes in this population.M…