Nature Communications, Published online: 22 June 2026; doi:10.1038/s41467-026-74592-x The development of catalytic systems for the enantioselective epoxidation of sterically hindered trisubstituted alkenes and the oxidation of sulfilimines to sulfoximines using molecular oxygen (O₂) as the terminal oxidant remains a formidable challenge. Here, the authors report a biomimetic bifunctional photocatalyst that integrates a chiral manganese center and a covalently tethered anthraquinone photosensitiz