Why Do Some Patients Remain Depressed Despite Multiple Treatments? One of the greatest challenges in psychiatry is treatment-resistant depression (TRD). Although many individuals with major depressive disorder respond to antidepressants, approximately one-third continue to experience significant symptoms despite multiple treatment... The post New Review Highlights the Emerging Role of the Microbiota–Gut–Brain Axis in Depression appeared first on Louis A. Faillace, MD, Department of Psychiatry an