Purpose To identify the key clinical and imaging clues on computed tomography (CT) and magnetic resonance imaging (MRI) that can suggest the diagnosis of hepatic AL amyloidosis, thereby improving diagnostic accuracy and timely recognition among peers. Methods We retrospectively analyzed the clinical, CT, and MRI findings of 10 patients with confirmed hepatic AL amyloidosis. Results The predominant clinical manifestations included hepatomegaly (10/10, 100%), abdominal distension (9/10, 90%), fati