
epidemiology

BackgroundCoagulopathy is a common risk factor in the occurrence of intraventricular hemorrhage (IVH) and subsequent poor neurological outcomes in preterm infants. The causal effect of fresh-frozen plasma (FFP) transfusion and IVH needed to be identified urgently.MethodsWithin the framework of target trial emulation (TTE), we mimic the process of a randomized controlled trial based on retrospecti…
BackgroundPrimary brainstem hemorrhage (PBH) is a severe, poorly-prognostic stroke subtype. Since single biomarkers cannot reflect global inflammatory status, we constructed a composite Inflammatory Burden Index (IBI) incorporating neutrophil-to-lymphocyte ratio (NLR), C-reactive protein-to-albumin ratio (CAR), and systemic immune-inflammation index (SII), and assessed its links with 90-day poor …

A long day spent sitting may affect health differently depending on how that sitting time is spread out. New research suggests that remaining sedentary for long, uninterrupted periods could be more concerning than the same amount of sitting broken up by regular movement. The study was led by Frederick Ho of the University of Glasgow […] The post Longer Sitting Time Linked to Higher Cancer Death R…
A systematic review of 11 observational studies representing more than 4.9 million patients found that GLP-1 receptor agonists were generally associated with neutral or potentially protective psychiatric outcomes, although one obesity-focused cohort reported increased risks of depression, anxiety, and suicidal behavior. Direct evidence for antidepressant effects remains limited, with only one cro…
Nature Sustainability, Published online: 26 August 2026; doi:10.1038/s41893-026-01927-3 Evidence from a multi-country analysis of 9.2 million cancer deaths suggests that traffic-sourced PM2.5 might contribute to the short-term PM2.5-related cancer mortality burden to a much greater extent than would be expected from its share of total PM2.5 concentration.
Nature Sustainability, Published online: 21 August 2026; doi:10.1038/s41893-026-01925-5 Cancer is an important public health concern globally, but whether cancer patients face increased risks of mortality from traffic-contributed air pollution is unclear. The authors assess the contributions of traffic-sourced fine particulate matter pollution to cancer mortality across eight countries from 2000 …

There's no effective treatment for dementia, and cases keep growing. The best bet at the...

Epidemiology: Microplastics Cause Lung Cancer Unless you are a cigarette smoker, you can't be 'inhaling' enough polypropylene and polyethylene to impact your lungs even if you live for 7,000 years. That doesn't stop fad claims that microplastics cause lung cancer. Hank Campbell Sun, 09/06/2026 - 06:29 Categories Chemistry
Surviving a stroke caused by bleeding in the brain is often only the beginning of a long recovery. Patients and their families must also live with the possibility that another stroke could occur in the future. A large research analysis now suggests that tighter control of high blood pressure can significantly reduce that danger. Importantly, […] The post A Stronger Blood Pressure Plan Could Prote…
Scientific Reports, Published online: 05 September 2026; doi:10.1038/s41598-026-69757-z Combined prognostic value of age at onset and socioeconomic status for long-term survival in metastatic breast cancer
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