BackgroundThoracolumbar compression fractures frequently coexist with depression, creating a self-reinforcing cycle of pain and psychological distress. Conventional nursing care offers limited psychological support for this comorbid population.MethodsThis quasi-experimental, descriptive study with a non-concurrent historical control enrolled 60 patients with comorbid depression and thoracolumbar compression fracture at a tertiary center in China. The control group (n = 30, February 2019 to March