The dual roles of uterine monocytes in regulation of tissue homeostasis throughout reproductive cycles in health and disease

Nature Immunology, Published online: 08 September 2026; doi:10.1038/s41590-026-02651-y Mann and colleagues reveal key roles for monocytes in replenishing the subsets of uterine macrophages involved in tissue remodeling and inflammation. These processes maintain tissue homeostasis in healthy reproductive cycles, but are disrupted in reproductive disease.