Nature Communications

Human brain seamlessly integrates multisensory stimuli to synthesize complementary information for enhanced perceptions, depending on neural principles of superadditivity, inverse effectiveness, and temporal congruency. Replicating multisensory integration in artificial intelligences has remained challenging due to the inefficiency of algorithmic fusions and the absence of hardware-native mechani…

Abstract The kinetics of charge separation in Photosystem II, initiated within the reaction center, remain debated due to spectral congestion and overlapping timescales with energy transfer. Here, by means of atomistic molecular dynamics and quantum dynamics simulations, we present a kinetic model that attributes the observed multi-exponential behavior of the primary charge separation step to wat…

Abstract Gardnerella species are key drivers of bacterial vaginosis (BV), a prevalent condition affecting nearly one in three women of reproductive age and associated with adverse reproductive outcomes. Despite decades of study, progress in defining Gardnerella diversity has been hindered by inconsistent taxonomy and poor-quality genomic resources. Here we sequenced 392 Gardnerella isolates spann…

Abstract Tanycytes are radial-glia-like cells that play important roles in regulating the neuroendocrine system and metabolism. Synapse-like (synaptoid) connections have previously been described between neurons and tanycytes, but their structure and function are unclear. Here, we report that neuron-tanycyte synaptoids are abundant and resemble typical neuronal synapses in shape and composition. …

Schiff bases, despite their structural versatility and broad applications, have remained elusive as acyclic atropisomers due to synthetic challenges. Herein, we report a palladium-catalyzed asymmetric N-allylation of diarylmethanimines with allylic precursors, enabling the construction of acyclic Schiff base atropisomers bearing C–C axes. Crucially, dynamic ligand exchange between the imine subst…

Molecular additives are frequently employed to enhance the performance of perovskite light-emitting diodes (PeLEDs), either through surface defect passivation or crystal growth control. In general, such passivation is attained through the chelation of the molecular additive to a defective Pb site along a lattice plane. Unfortunately, nano-crystallites often display multiple lattice planes and def…

Abstract Optical physical unclonable functions provide artificial fingerprints through randomized light–matter interactions, but are limited by static architectures that lack adaptive defense capabilities. Although reconfigurable optical physical unclonable functions based on phase-change materials have been proposed to overcome this constraint, their reliance on light or heat makes them suscepti…

Abstract Plasmodium falciparum possesses one of the most AT-rich genomes in nature (80.6%). A consequence is an asparagine-rich proteome. A quarter of P. falciparum proteins possess poly-asparagine repeats that can extend more than 100 residues. The role of these repeats has remained a mystery in the biology of this parasite. Here, we report that the poly-asparagine repeat-containing Nterminus of…