[Gut Microbes] The authors found that Agathobacter rectalis (Ar) suppressed colorectal cancer cell growth, clonogenicity, migration, and cell cycle progression. They identified (−)-epigallocatechin (EGC) as an Ar-derived metabolite that recapitulated Ar-mediated anti-CRC effects, defining an Ar–EGC microbe–metabolite axis.
Agathobacter rectalis Suppresses Colorectal Tumorigenesis via an Epigallocatechin-SREBF2 Axis Controlling Cholesterol Metabolism
Makenna Cameron

