biology

Sleep is an essential biological function with unclear mechanisms. Recent research links the circadian clock, energy metabolism, calcium handling, reactive oxygen species (ROS) production, and synaptic plasticity to cognitive performance. Given that mitochondria regulate cellular energy production, calcium buffering, and ROS dynamics, it stands to reason that mitochondrial function plays a signif…

Nature Communications, Published online: 07 September 2026; doi:10.1038/s41467-026-76570-9 T cell proliferative capacity and persistence are key determinants of CAR-T cell therapeutic efficacy. Here, the authors show that CAREp, a microparticle-based platform displaying CAR-targeting antigens and CD28-costimulatory antibodies, selectively and sustainably expands human CD8+ CAR-T cells while maint…

All known life on Earth stores genetic information using the same four-letter DNA alphabet. Researchers have now shown that one of biology’s most important enzymes can accurately read an artificial DNA system containing eight letters. The discovery suggests that the natural machinery inside living cells may be able to work with a much larger genetic […] The post Natural Enzyme Successfully Reads …

The clouds of Venus may seem like one of the last places where the building blocks of life could survive. They consist mostly of concentrated sulfuric acid, a highly corrosive substance capable of dissolving metals and destroying many biological molecules found on Earth. However, a new study suggests that some important molecules may be surprisingly […] The post Building Blocks of Life Can Fold a…

Researchers at Asfendiyarov Kazakh National Medical University (KazNMU) have identified biologically active compounds with antiviral, antimicrobial, and anti-inflammatory effects in several plant species native to Kazakhstan, providing new chemical and experimental data on medicinal flora from Central Asia.

Researchers at Asfendiyarov Kazakh National Medical University (KazNMU) have identified biologically active compounds with antiviral, antimicrobial, and anti-inflammatory effects in several plant species native to Kazakhstan, providing new chemical and experimental data on medicinal flora from Central Asia.

Renal anemia is one of the most common complications of chronic kidney disease (CKD). This study investigated gut microbiota composition and fecal/plasma short-chain fatty acids (SCFAs) in 30 non-dialysis renal anemia patients and 20 healthy controls. Gut microbiota was assessed by 16S rRNA gene amplification sequencing and SCFAs were measured using gas chromatography-tandem mass spectrometry (GC…

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