ObjectiveBoth the C-reactive protein (CRP)–triglyceride–glucose index (CTI) and the systemic immune-inflammation index (SII) are easily accessible, cost-effective, and rapid indices derived from biochemical examinations. The study aimed to identify the roles of the CTI and SII in older adults with comorbid obstructive sleep apnea (OSA) and depression.MethodsThe study included 52 older patients with depression coexisting with OSA and 108 patients with depression but without OSA. The CTI was calcu