Accurate detection and localization of early-stage breast cancer represent the cornerstone for improving cancer cure rates and extending patient survival. However, selecting therapeutic regimens characterized by high efficacy and minimal side effects remains a formidable clinical challenge. Combining these two goals is now feasible with the innovation and progress of nanomaterials. Herein, we designed and synthesized a novel nanomaterial PDA@Fe-BTC@ MnO2 nanoparticles (PFMPP NPs) for breast canc