transplantation

Organ kept Tim Andrews off dialysis and acted as a ‘bridge’ while he waited for a human transplant in the US A genetically modified kidney from a pig called Wilma has kept a 66-year-old man with kidney failure alive for a record nine months and successfully acted as a “bridge” to a human transplant in a world first. Tim Andrews was seriously ill with end-stage kidney disease caused by type 2 diab…

A new risk stratification model developed by Northwestern Medicine scientists may help better identify patients who have a lower risk of kidney transplant rejection, which can inform more personalized treatment and care strategies that present fewer adverse side effects, as detailed in a recent study published in Nature Communications. The post Identifying Patients at Lower Risk for Kidney Transp…

The Hidden Organ Transplant Threat — CMV — Dr. Neil Inhaber, MD, FRCPC — Head, Marketed Products and Neuroscience, Global Medical Affairs, Takeda. Every year, hundreds of thousands of people around the world receive life-saving organ transplants — new hearts, kidneys, lungs, and livers that offer patients a second chance at life. But transplantation is […]

Today, the University of Colorado Anschutz announced the creation of the Division of Transplant Medicine within the Department of Medicine, the first of its kind in the nation. The new division brings transplant specialists together in a new academic model designed to strengthen patient care, accelerate discovery and train the next generation of transplant leaders.

BackgroundTacrolimus (TAC) exhibits high pharmacokinetic variability post-liver transplantation (LT). Traditional models overlook the metabolic chimerism between recipient (intestinal) and donor (hepatic) genotypes. We aimed to evaluate a combined donor–recipient CYP3A functional allele count predicting TAC exposure.MethodsThis retrospective study analyzed 1,350 TAC trough measurements from 99 LT…

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