Frontiers in Veterinary Science | New and Recent Articles

IntroductionSoft-shelled eggs are a major eggshell defect in poultry production, yet the underlying mechanisms of their formation remain unclear. The objective of this study was to characterize biological changes associated with soft-shelled egg formation in laying hens by integrating quantitative proteomics and untargeted metabolomics analyses of uterine fluid (UF), combined with morphological a…

IntroductionNewcastle Disease Virus (NDV) is not only a significant and persistent threat to the healthy development of poultry industry, but also an important pathogen endangering food safety and harboring potential zoonotic risks.MethodsIn this study, a rapid and highly sensitive diagnostic assay was established for genotype VII NDV by integrating reverse transcription recombinase polymerase am…

IntroductionThe objective of this study was to evaluate the tolerability and efficacy at 3 months of intravenous (IV) allogeneic uterine-derived mesenchymal stromal cells (UMSCs) for osteoarthritis (OA) in client-owned cats.MethodsThis was a randomized, masked, placebo-controlled pilot study conducted across six veterinary clinics. Thirty-five client-owned cats with naturally occurring OA were ra…

BackgroundDystocia is an uncommon but potentially life-threatening complication of equine parturition. Due to early separation of the chorioallantois during the expulsive stage, fetal oxygen supply rapidly becomes compromised, making dystocia a time-critical emergency for both mare and foal. Objectives: To describe obstetrical interventions performed at equine referral hospitals, evaluate mare an…

Accurate recognition of pig behavior plays a critical role in enhancing animal welfare and management efficiency for precision livestock farming. Nevertheless, existing methods are commonly limited by rigid feature fusion strategies, insufficient preservation of spatial details, and weak interactions across hierarchical features, which severely compromise recognition performance in complex farm s…

A 3.5-year-old, 5.2-kg mixed-breed dog was presented with persistent stranguria after being neutered due to dystocia 6 months ago. Plain abdominal radiographs revealed an intrapelvic soft-tissue attenuating mass that displaced the urinary bladder cranially and constricted the descending colon. Abdominal ultrasonography yielded inconclusive results. Computed tomography revealed the mass as a tubul…

IntroductionEnvironmental stressors in animal shelters may lead to development of excessive arousal, posing risks to adoptability and behavioral euthanasia. Recommendations regarding excessive arousal in shelter dogs include providing pharmaceuticals and enrichment.MethodsA randomized controlled trial was conducted to assess the influence of enrichment and pharmaceutical interventions on shelter …

Salmonella remains an important pathogen in swine production due to its impact on animal health and its role in foodborne illnesses. However, routine surveillance in pigs relies largely on fecal sampling, which can be labor-intensive and difficult to scale across large production systems. This study aimed to develop and evaluate a novel approach for monitoring Salmonella in finisher pigs using or…

BackgroundThe integration of Extended Reality (XR) technologies into animal-handling training provides science students working with animals in experimental research with an innovative platform for developing practical and ethical skills that contribute to medical advancement. As laboratory practices become increasingly globalized and guided by the 3Rs principle of Replacement, Reduction, and Ref…

Static posturography is widely used to assess postural stability in dogs. Considerable methodological variation exists regarding whether center of pressure (COP) parameters are derived from whole-body, forelimb-, or hindlimb-based measurements and whether values are expressed as absolute or base of support (BOS)-normalised parameters. The aims were to examine the associations between whole-body, …

IntroductionPorcine reproductive and respiratory syndrome (PRRS) is an economically devastating viral infection in pigs that results in estimated losses of $1.2 billion annually. Control of porcine reproductive and respiratory syndrome virus (PRRSV) has been challenging due to the weak and delayed development of adaptive immunity to the virus. This has been partially attributed to the low inducti…

IntroductionApolipoprotein E (ApoE), secreted by astrocytes and microglia after neuronal injury, is involved in neuronal regeneration and modulation of inflammatory processes. Inverse associations between ApoE and the proinflammatory mediator C-reactive protein (CRP) are described in mice, but knowledge in dogs is limited.MethodsThis study investigated ApoE levels in cerebrospinal fluid (CSF) fro…

BackgroundElbow dysplasia is a leading cause of forelimb lameness in medium- to large-breed dogs, and computed tomography (CT) is the imaging modality of choice for assessment of the medial coronoid process. Image quality depends on patient positioning and tube current, but their effects have not been systematically compared.AimsTo compare the image quality of two canine elbow CT positioning prot…

Cutaneous manifestations of feline leishmaniosis may occur at anatomical sites commonly affected by squamous cell carcinoma (SCC), creating potential diagnostic overlap. Although concurrent Leishmania infection and SCC have been described in individual cats, the presence of parasite DNA in feline SCC tissue has not been systematically investigated. This retrospective cross-sectional study evaluat…

IntroductionTransforming Growth Factor-β (TGF-β) has been implicated for its role in fibrosis and progression of chronic kidney disease (CKD) in both humans and rodents. Additionally, CKD is a common and progressive condition in canines, with striking pathological similarities to human disease. However, targeted therapies addressing fibrogenic mediators in dogs remain underexplored.MethodsWe inve…

IntroductionEpilepsy is a common neurological disorder in dogs. Autonomic manifestations are commonly recognised but poorly reported in veterinary literature. This study aimed to determine owner reported prevalence and course of autonomic signs in epileptic dogs.MethodsA survey for owners of dogs with epilepsy created with Qualtrics was circulated on Facebook between March 2025 and August 2025.Re…

Non-contact temperature assessment is highly valuable for screening animal populations, but its performance can be influenced by various external and biological variables. This study aimed to quantify the association between eye temperature (ET) and rectal temperature (RT) in dogs, and to identify physiological and environmental factors associated with these readings. Field study: ET was obtained…

Burnout is an occupational phenomenon resulting from poorly managed chronic workplace stress, and veterinary medicine is among the professions at highest risk. Veterinarians working with exotic animals represent a specialised professional subgroup whose wellbeing may affect the availability of dedicated care for non-traditional species. To our knowledge, no study has examined burnout in this popu…

Swimmer puppy syndrome (SPS) is a rare developmental condition of unknown etiology. The syndrome is characterized by a puppy’s inability to adduct the limbs, resulting in lateral limb abduction and an inability to stand or walk. In this case, an almost 4-week-old female Golden Retriever presented for early physiotherapeutic evaluation. Adduction tapes were applied to the forelimbs and hindlimbs. …