Nature Microbiology
Nature Microbiology, Published online: 15 September 2026; doi:10.1038/s41564-026-02479-0 Environmental temperature can be accurately inferred from the DNA composition of microbial communities across marine and soil ecosystems, using machine learning and based on tetranucleotide frequencies. GC content shows an opposing trend to temperature in these environments, associated with differences in nut…
Cryo-EM structures of Candida albicans chitin synthase Chs1 reveal a druggable translocation channel
Nature Microbiology, Published online: 15 September 2026; doi:10.1038/s41564-026-02485-2 Structures of Candida albicans class II chitin synthase reveal mechanisms of oligosaccharide translocation and inhibition. The translocation channel is a class II-specific druggable site, and its inhibitor synergizes with a class I inhibitor.
Nature Microbiology, Published online: 15 September 2026; doi:10.1038/s41564-026-02490-5 An enrichment culture from hot spring sediments in China suggests that Ca. M. sphaerolipidus uses a suite of metabolic pathways to convert long-chain fatty acids such as oleic acid to methane, a process they term liparotrophy.
Nature Microbiology, Published online: 14 September 2026; doi:10.1038/s41564-026-02495-0 To successfully translate microbiome knowledge into practical interventions for farmers, research must be designed with agriculture in mind and shift from retrospective observation to predictive actions.
Nature Microbiology, Published online: 14 September 2026; doi:10.1038/s41564-026-02458-5 Air quality and climate factors alter the risk of invasive pneumococcal diseases such as meningitis. Importantly, the lineage and serotype (population structure) of circulating bacteria can alter how quickly disease risk rises in the weeks following exposure.
Nature Microbiology, Published online: 14 September 2026; doi:10.1038/s41564-026-02488-z Air pollution increases the risk of invasive pneumococcal disease and bacterial lineage changes the timing of that risk, making pathogen genomic diversity an effect modifier.
Nature Microbiology, Published online: 09 September 2026; doi:10.1038/s41564-026-02503-3 Author Correction: Longitudinal plasma metabolomics reveals a role for taurine in asymptomatic malaria and seasonal persistence
Nature Microbiology, Published online: 09 September 2026; doi:10.1038/s41564-026-02504-2 Publisher Correction: Unique adaptations in sulfatases underpin colonic mucin degradation by Akkermansia muciniphila
Nature Microbiology, Published online: 03 September 2026; doi:10.1038/s41564-026-02474-5 Integron insertion sites engineered into counterselection markers allow large-scale and high-throughput capture of integron-encoded genes from genetically tractable bacteria or DNA samples.
Nature Microbiology, Published online: 03 September 2026; doi:10.1038/s41564-026-02466-5 Researchers identify interleukin-17A+ γδ T cells as key immune defenders against non-tuberculous mycobacteria infections, demonstrating their ability to protect hosts when IFNγ immunity is impaired.
Nature Microbiology, Published online: 03 September 2026; doi:10.1038/s41564-026-02464-7 Inhibition of the pro-survival protein BCL-2 at the initiation of antiretroviral therapy in macaques reduced persistent viral reservoirs in both blood and lymph nodes during SIV infection.
Nature Microbiology, Published online: 02 September 2026; doi:10.1038/s41564-026-02462-9 Grounding microbial conservation in ecological principles
Nature Microbiology, Published online: 02 September 2026; doi:10.1038/s41564-026-02463-8 Reply to ‘Grounding microbial conservation in ecological principles’
Nature Microbiology, Published online: 01 September 2026; doi:10.1038/s41564-026-02472-7 MetaCAT is a computational framework to assess host–microbiome interaction via a combination of high-accuracy and efficient microbial genome reconstruction and metagenome-wide association studies with the host physiology using metagenomics data.
Nature Microbiology, Published online: 01 September 2026; doi:10.1038/s41564-026-02489-y Platforms for community-led but globally connected knowledge and resource sharing can move us towards more equitable and more effective research and solutions for infectious diseases.
Nature Microbiology, Published online: 31 August 2026; doi:10.1038/s41564-026-02461-w The journey of Mycobacterium tuberculosis between hosts in aerosol droplets has often been viewed as a passive phase in its life cycle. Recent evidence shows that the inevitable desiccation associated with aerosol transmission triggers a program that imperfectly repairs DNA damage, generating genetic diversity a…
Nature Microbiology, Published online: 27 August 2026; doi:10.1038/s41564-026-02439-8 A randomized controlled trial shows that autodissemination stations reduce egg counts for Aedes notoscriptus, the Mycobacterium ulcerans vector, with exploratory analyses suggesting that the intervention could also reduce human Buruli ulcer cases caused by these bacteria, in intervention areas in Melbourne, Aust…
Nature Microbiology, Published online: 27 August 2026; doi:10.1038/s41564-026-02496-z Author Correction: Multikingdom and functional gut microbiota markers for autism spectrum disorder
Nature Microbiology, Published online: 27 August 2026; doi:10.1038/s41564-026-02481-6 Synthetic microbiology has the potential to transform microorganisms into engineered tools for a sustainable future. Nature Microbiology aims to be a platform for sharing innovative breakthroughs and constructive dialogue around the promise and pitfalls of the field.
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