allergy

[Nature Communications] Scientists investigated the function of CD97/ ADGRE5 , expressed in mouse and human immune and lung epithelial cells, in allergic asthma. A single CD97 antibody treatment before allergen sensitization worsens allergic responses, highlighting a role for CD97 in early immune regulation.

Nature Communications, Published online: 28 August 2026; doi:10.1038/s41467-026-76948-9 Allergic asthma involves different lung cells and mediators. Here, the authors examine the function of CD97/ADGRE5 and show that its absence increases the severity of allergic lung inflammation in mice. Allergen-pulsed Cd97-/- DCs are more activated and promote stronger type 2 immune responses than WT DCs and,…

Allergic rhinitis and asthma are among the most common chronic diseases today, affecting hundreds of millions of people worldwide.

Some 33 million Americans have severe food allergies. Now, researchers at Boston Children's Hospital may have found a promising solution.

Nature, Published online: 05 August 2026; doi:10.1038/d41586-026-02440-5 Existing treatments for food allergy are limited.

Altering the gut microbiomes of people with peanut allergy using faeces donated from an allergy-free individual improved their peanut tolerance in a clinical trial

Omalizumab demonstrates higher treatment success for multifood allergies compared to oral immunotherapy, with fewer adverse events impacting patient retention.

Researchers at the Icahn School of Medicine at Mount Sinai have been awarded a five-year, $7.2 million grant from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), to establish a new Asthma and Allergic Diseases Cooperative Research Center focused on advancing personalized treatment strategies for peanut allergy.

For decades, scientists have known that allergic asthma is caused by an overactive immune system, but many of the tiny biological switches controlling this process have remained hidden. Researchers at National Jewish Health have now uncovered one of those switches, offering fresh hope for future asthma treatments. Their study, published in Science Advances, centers on […] The post Unexpected Caus…

Allergic rhinitis (AR) is a common disease around the world, mediated by type 2 immune responses, and some patients don’t respond well to current standard treatments. This shows AR isn’t a single type of disease but a complex syndrome caused by different internal body mechanisms. Periostin is a key matrix protein sitting downstream of the interleukin-4 (IL-4) and interleukin-13 (IL-13) pathways, …

A Swedish randomized trial found that slow up-dosing peanut oral immunotherapy with a low maintenance dose helped 82% of preschool children achieve sustained peanut tolerance after three years. The approach proved safer than conventional protocols, with severe reactions uncommon and strong family adherence throughout treatment.

By discovering and describing anaphylaxis, Richet revealed how the immune system can produce extreme, sometimes fatal reactions to previously encountered substances, laying the foundation for modern allergy and immunology research

Scientific Reports, Published online: 24 April 2026; doi:10.1038/s41598-025-19978-5 Association of the CD14 gene rs2569190 polymorphism with the risk of allergic rhinitis: a systematic review and meta-analysis

Discover how introducing peanuts at 4-6 months can reduce allergy risk by 71% into adolescence. Learn about the LEAP-Trio study, diagnosis, and new FDA treatments. The post Peanut Allergy Prevention: Early Introduction & Lasting Protection appeared first on THE SCIENCE NOTES .

Schematic overview of preclinical data from Ze 339. (Details at the end of the article) More and more people around the world are dealing with allergic rhinitis, a condition that causes sneezing, stuffy nose, and itchy eyes. Experts say this is partly due to changes in the environment and how people live today. Traditional allergy medications like antihistamines are helpful but can make people fe…

This little-known allergy, known as alpha-gal syndrome, is potentially deadly. Here’s what we know about it — and how to avoid the tick bites that seem to cause it.