aging

Insilico Medicine ("Insilico"), a clinical-stage company focused on generative AI-driven drug discovery and development, today announced the publication of a new study conducted in collaboration with an international team of scientists from Harvard Medical School, Stanford University, The Broad Institute, RWTH Aachen University, Peking University and Westlake University.

Nature Reviews Drug Discovery, Published online: 07 September 2026; doi:10.1038/s41573-026-01514-3 There are currently no approved therapies for sarcopenia, the age-related loss of skeletal muscle mass and strength. This Review discusses advances in understanding of the cellular, molecular and metabolic mechanisms driving muscle wasting with ageing, while assessing emerging therapeutic approaches…

Metformin has been used for decades to help people with type 2 diabetes control their blood sugar. Now scientists are asking a much bigger question: could this common, inexpensive medicine also help the body age more slowly? A recent scientific review brought together decades of research on metformin, ranging from experiments in cells and animals […] The post Could Diabetes Drug Metformin Help Yo…

The age a woman goes through menopause could predict her long-term neurological health. A new study links early menopause to faster cognitive decline, suggesting the transition is a vital window for protecting the brain.

A 24-week pilot randomized trial found that both traditional Hatha yoga and a faster, cognitively demanding YogaCue program were associated with improvements in cognitive and physical performance in independently living older adults. YogaCue showed promising additional gains in verbal and episodic memory, aerobic fitness, and lower-body power, although the small study could not establish clear su…

Four Weeks of a Vegan Diet Alter Signs of Inflammation and Aging Nutrition study involving 48 healthy adults / Researchers analyze more than 800,000 genetic loci / Evidence of changes in inflammatory processes, metabolism, and biological aging Just four weeks of dietary changes can already be reflected in epigenetic changes. This is shown by a study conducted by theUniversity Center for Naturopat…

A large study involving more than 270,000 people has linked higher blood levels of the amino acid tyrosine to a shorter lifespan in men. Using both observational data and genetic analysis, researchers found that elevated tyrosine could potentially reduce male life expectancy by nearly a year, while no significant effect appeared in women. Tyrosine is found naturally in protein-rich foods and is a…

Older adults at risk of dementia improved their memory and thinking after following lifestyle programs combining exercise, healthy eating, cognitive training, and social engagement. Those who received regular coaching and structured support improved substantially more than participants given general health advice.

A medicine found in pharmacies around the world is attracting attention from scientists who study aging. Metformin, best known as a treatment for type 2 diabetes, may affect biological processes that influence how quickly the body grows old. The idea is appealing because metformin is not a futuristic drug developed specifically for longevity. Doctors have […] The post An Old Diabetes Drug May Hel…

Aging skin is often discussed in terms of wrinkles, spots and changes in appearance. Scientists, however, see something much more complex. Skin is a living organ filled with immune cells, helpful and potentially harmful microbes, proteins and chemical signals that constantly respond to the world around us. Researchers are now asking whether these changes could […] The post Your Skin May Show Your…

Imagine being 50 and watching your biological age fall to 45. Five years younger, according...

After analysing 25,000+ tissue samples, researchers conclude that there are two crucial stages in life when you age faster than other times.

Age-related molecular scores rose after emergency surgery, across pregnancy and during critical illness, then fell with recovery. The clocks are dynamic biomarkers, not proof that accumulated ageing was erased.

Nature Communications, Published online: 05 September 2026; doi:10.1038/s41467-026-77379-2 Osteoclasts need to manage reactive oxygen species by coordinating redox control and mitochondrial quality maintenance. Here, the authors identify OXR1 as a regulator of osteoclastogenesis and mitophagy, and show that genetic or pharmacological targeting of OXR1 attenuates bone loss in an osteoporosis mouse…

A sore knee can start as a small annoyance and gradually become a problem that changes how a person lives. For millions of adults, the cause is osteoarthritis, a common joint disease that can affect work, sleep, exercise and even emotional well-being. The knee carries much of the body’s weight whenever a person stands, walks […] The post Why Knee Arthritis Is Not Just an Aging Problem appeared fi…

Scientific Reports, Published online: 05 September 2026; doi:10.1038/s41598-026-69225-8 TNF-α and IFN-γ induce neurotoxicity in human iPSC-derived astrocytes that is enhanced by aging

Twisting movements are a part of everyday life. These exercises can help you do them with ease and control.