analytical-chemistry

Scientific Reports, Published online: 21 June 2026; doi:10.1038/s41598-026-56693-1 Hydrophilicity-switchable deep eutectic solvent-based ultrasound-assisted liquid-phase microextraction for the green and efficient spectrofluorimetric determination of verapamil in human plasma

The colorimeter is an important scientific instrument used to measure the concentration of colored substances in a solution by analyzing how much light the solution absorbs. Today, colorimeters are widely used in chemistry, biology, medicine, environmental science, and industry. Their development over more than a century has greatly improved the accuracy and efficiency of chemical analysis. The h…

Scientific Reports, Published online: 19 June 2026; doi:10.1038/s41598-026-58798-z Anionic surfactant reformed carbon composite voltammetric sensor for the efficient and sensitive detection of carmoisine in food samples

Metanephrine (MN) and normetanephrine (NMN) are critical biomarkers for neuroendocrine tumors (pheochromocytoma and paraganglioma). Following our previous development of a molecularly imprinted solid-phase extraction (MISPE) sorbent for urine analysis, this study evaluated MISPE coupled with HILIC-MS/MS for determining metanephrines in human plasma. Unlike conventional phases, the novel polymer s…

Many people rely on the sniff test to decide whether food is still safe to eat. If milk smells fine or leftovers don’t seem off, we often assume they are okay. But the human nose isn’t always reliable. Every year, millions of people in the United States become sick from food-borne germs that can grow […] The post New electronic ‘nose’ can tell when your food is spoiled appeared first on Knowridge…

Herein, two new azo reagents, 2-[(1-banzimidazol)azo]-2-hydroxy-5-banzal (BIApB) and 6-[(1-banzethiazol) azo thymol] (BTAT), were synthesized and identified using FTIR, UV-Vis, mass spectrometry, and ¹H-NMR. Also, this research presents a comparative analysis of novel azo-chelating reagents for the cloud point extraction (CPE) of gold complexes. The study evaluates how the structural differences …

IntroductionPotato virus S (PVS) causes severe damage to Solanaceae plants, especially potato, due to its widespread infection and the reliance on laboratory-based reverse transcription-polymerase chain reaction (RT-PCR) testing. This work intends to develop a rapid, highly sensitive, and dual-signal platform for on-site PVS detection.MethodsWe developed a highly sensitive lateral-flow immunoassa…

Earlier this spring, the Notre Dame Sensor Initiative (NDSI) installed two new instruments in the Analytical Science and Engineering (ASEND) core facility, made possible with funding from the Bioengineering and Life Sciences (BELS) Initiative and support from Notre Dame Research. A new permanent acquisition, a Shimadzu LCMS-8050 Triple Quadrupole Mass Spectrometer, is engineered for fast, high-se…

Coffee is a key ingredient in the scientific process for many researchers, so it’s no wonder that researchers often develop an interest in the drink’s physics and chemistry. In a new study, a research team devised an objective method to test both a coffee’s strength and its roast color. The researchers used a potentiostat to […]

Quaternary ammonium compounds (QACs) are widely used in consumer products and industrial processes as disinfectants. In water resource recovery facilities, a substantial portion of QACs reside with solids, and thus pass through anaerobic digesters. As antimicrobial agents, QACs present a potential risk to digester operation, yet we have limited understanding of their toxicity to this unit operati…

Multi-isotope calibration (MICal) was evaluated as an alternative quantitative strategy for multi-elemental determination by inductively coupled plasma mass spectrometry (ICP-MS) in complex agroalimentary matrices. Infrared-assisted digestion (IRAD) was employed as a rapid and acid-efficient sample preparation approach. Method performance was assessed using certified reference material and furthe…

This study aimed to adapt and validate the QuEChERS method for extracting and purifying 19 persistent organic pollutants—11 organochlorine compounds and 8 polychlorinated biphenyls—for GC–MS (CNI mode) analysis in bird liver samples. After extraction with acetonitrile and salt phase separation, the extract was reconstituted in hexane and cleaned using sulfuric acid. Linearity was ≥0.9, and precis…

Scientific Reports, Published online: 11 June 2026; doi:10.1038/s41598-026-57405-5 Analytical comparisons for solving the modified fractional Kawahara equation: application on numerical simulation of chemical signaling processes