obesity

When doctors talk about obesity and type 2 diabetes, they often focus on blood sugar levels, body weight, and cholesterol. Yet one of the greatest dangers of these conditions is the damage they cause to blood vessels. This damage can quietly develop over many years and eventually lead to heart attacks, strokes, and other serious […] The post Hidden Fat Around Blood Vessels Could Hold the Key to P…

The obesity treatment landscape is changing fast, with GLP-1 drugs opening the door to more effective care than ever before. Experts now envision a future where medications, minimally invasive procedures, surgery, and precision medicine work together to deliver better long-term results.

Medicines that help people lose weight have transformed the treatment of obesity in just a few years. Many people who struggled with weight for decades are now losing amounts of weight that were previously difficult to achieve without surgery. Among the most widely used treatments are a group of medicines called GLP-1 drugs. These medicines […] The post Which Weight-Loss Drug Works Best? appeared…

People taking popular GLP-1 weight-loss drugs like Ozempic, Wegovy, Mounjaro, and Zepbound may be shedding pounds, but a new study suggests they are also moving less. People with obesity who lost weight while taking popular medications such as Ozempic, Wegovy, Zepbound, and similar drugs became significantly less physically active, according to research presented at ENDO [...]

Weight-loss medicines such as semaglutide and tirzepatide have become some of the most talked-about drugs in the world. Their brand names, including Ozempic, Wegovy, Rybelsus, Mounjaro, and Zepbound, are now familiar to millions of people. They are often described as breakthrough treatments because many patients have achieved weight loss that was previously difficult to reach […] The post Why Som…

Start with a number that ought to give the whole boom pause: within a year of starting one of the new weight-loss injections, roughly two-thirds of people taking them for obesity alone have stopped. Sixty-five percent, give New! Sign up for our email newsletter on Substack.

The rapid rise of GLP-1 medications such as semaglutide and tirzepatide has transformed obesity treatment.

Obesity has become one of the biggest health challenges of modern times. Around the world, rising body weight is linked to higher risks of type 2 diabetes, heart disease, sleep problems, certain cancers, and many other medical conditions. For years, people trying to lose weight often struggled because lifestyle changes alone do not always produce […] The post Two Popular Weight-Loss Drugs Show Ve…

Tirzepatide doesn't just help people lose weight; it also activates brown adipose tissue, representing a major milestone in obesity research, according to a study being presented Monday at ENDO 2026, the Endocrine Society's annual meeting in Chicago, Ill.

Glucagon-like peptide-1 receptor agonists (GLP-1RAs) have become massively popular for weight loss, but results vary from person to person and drug to drug.

One of the largest real-world studies of people taking GLP-1 medications found women, those without pre-existing conditions such as type 2 diabetes and high blood pressure, and behavioral factors such as previously setting a weight goal were the best predictors of total weight loss, according to a study being presented Monday at ENDO 2026, the Endocrine Society's annual meeting in Chicago, Ill.

The American College of Physicians (ACP) has issued a new living clinical guideline to help physicians choose medications with lifestyle modifications to manage overweight and obesity in adults.

Tirzepatide doesn't just help people lose weight; it also activates brown adipose tissue, representing a major milestone in obesity research, according to a study being presented Monday at ENDO 2026, the Endocrine Society's annual meeting in Chicago, Ill.

Metabolic and bariatric surgery for teens with severe obesity was found to be cost-effective over 10 years, according to the new analysis from Ann & Robert H. Lurie Children's Hospital of Chicago published in JAMA Network Open.

GLP 1s do not harm male hormones or fertility after long-term use, according to a study being presented Monday at ENDO 2026, the Endocrine Society's annual meeting in Chicago, Ill. In fact, the research team found GLP-1s may improve testosterone levels and sperm quality in men with obesity related low testosterone, while also addressing the underlying effects of obesity.

Adults with obesity losing weight with glucagon-like peptide-1 (GLP-1) receptor agonist medications significantly decreased their physical activity, which is essential to protect muscle, according to a study being presented Saturday at ENDO 2026, the Endocrine Society's annual meeting in Chicago, Ill.

Cardiovascular-kidney-metabolic syndrome, often called CKM syndrome, is a relatively new term that many people have never heard of. Yet health experts believe it may become one of the most important health concepts of the coming decades. CKM syndrome is not a single disease. Instead, it describes the close connection between excess body fat, diabetes, heart […] The post CKM Syndrome: The Hidden L…

Once-daily oral elecoglipron produced dose-dependent weight loss in adults with obesity or overweight without diabetes, with mean reductions reaching 10.5% at 26 weeks and 11.8% at 36 weeks in the highest-dose weekly-titration group. The phase 2 trial found no evidence of a weight-loss plateau by 36 weeks, while gastrointestinal adverse events were common but generally manageable.

A newly developed pill may offer a completely different way to treat type 2 diabetes and obesity, according to research published in the journal Cell. Scientists from Karolinska Institutet and Stockholm University say the experimental treatment could help people improve blood sugar control and lose unhealthy body fat without some of the drawbacks seen with […] The post New Diabetes Pill Could Hel…

The rise of weight-loss injections has transformed obesity treatment in a way few experts predicted just a few years ago. Medications such as Wegovy, Ozempic, Zepbound, and Mounjaro have helped many people lose substantial amounts of weight when diet and exercise alone were not enough. Now, researchers have uncovered evidence suggesting that these medicines may […] The post Could Weight-Loss Inje…