ophthalmology

Inherited retinal dystrophies (IRDs) represent heterogeneous genetic eye disorders frequently linked to RPE65 mutations. Voretigene neparvovec (VN, Luxturna), an AAV2-mediated gene therapy, remains the sole approved drug for biallelic RPE65-associated IRDs. This study presents 3-, 6- and 22-month follow-up findings of the first mainland Chinese patient with compound heterozygous RPE65-related Leb…

Nation's largest physician organization adopts policy calling for insurance coverage for treatments that can slow its progression in children.

Gene Therapy, Published online: 02 September 2026; doi:10.1038/s41434-026-00640-2 Optogenetic vision restoration: translational barriers and emerging therapeutic strategies

Joel S. Schuman, MD, FACS, has been selected as the recipient of the 2027 RPB David F. Weeks Award for Outstanding Vision Research for his transformative contributions to ophthalmic imaging, glaucoma research, and vision science.

Dry eyes are a very common chronic eye condition among women in perimenopause and beyond. Here's why you shouldn't ignore it.

Scientific Reports, Published online: 30 August 2026; doi:10.1038/s41598-026-68699-w Effect of residual spherical equivalent on visual outcomes of trifocal intraocular lens implantation in patients with cataracts across different refractive states

BackgroundIntravenous methylprednisolone pulse (IVMP) therapy is the first-line treatment for active moderate-to-severe and very severe thyroid-associated ophthalmopathy (TAO). IVMP-induced sinus bradycardia has not been previously reported in patients with TAO in the published English-language literature. This study aimed to determine the prevalence and characteristics of IVMP-induced bradycardi…

PurposeTo determine which subgroup of children would best benefit from 0.01% atropine eyedrop.MethodsThis post hoc secondary analysis assessed 68 subjects. Placebo for the first year and 0.01% atropine eye drops for the second year. According to the annual spherical equivalent progression (SEP) during the first year, subjects were subdivided into three groups: slow, moderate and fast (annual SEP …

A dual stem cell scaffold improved vision and eye surface scores in a small first-in-human trial for aniridia-related keratopathy. For people with ARK (aniridia-related keratopathy), progressive damage to the eye’s surface can gradually cloud the cornea and severely reduce vision. In a first-in-human clinical trial at Moorfields Eye Hospital and University College London (UCL), a […]

The editorial was authored by Jacque L. Duncan, MD, professor of ophthalmology and chair of the Department of Ophthalmology, University of California, San Francisco, who did not participate in the PRIMA study. In a press release issued by Science Corporation, the company described the implant as “consisting of a tiny wireless chip implanted in the […]

A dual stem cell scaffold improved vision and eye surface scores in a small first-in-human trial for aniridia-related keratopathy. For people with ARK (aniridia-related keratopathy), progressive damage to the eye’s surface can gradually cloud the cornea and severely reduce vision. In a first-in-human clinical trial at Moorfields Eye Hospital and University College London (UCL), a [...]

Glaucoma is an eye disease that causes progressive damage to the optic nerve, leading to loss of sight. One major risk factor is an increase in intraocular pressure (IOP), or the pressure inside the eye.

While Bausch + Lomb’s dual-action eye drops failed to outperform active comparators at day 29, the investigational asset showed significant superiority at day 15.

Learn how thyroid eye disease is monitored, the difference between active and chronic phases, recommended tests, and when to seek urgent medical attention.

Nature, Published online: 24 August 2026; doi:10.1038/d41586-026-02616-z Injection of a person’s own mitochondria into the retina was safe but had only a temporary effect on restoring vision.

FRIDAY, Aug. 21, 2026 — Tammy Chalala, a retired dietitian in New York, was thrilled with the results of her cataract surgeries, which left her with close to 20/20 vision.She said she paid nearly $4,000 out-of-pocket for her two surgeries last year...

The pathogenesis of maculopathy remains incompletely understood, and emerging evidence implicates the gut–eye axis in retinal and macular diseases. Given that antibiotics with anti-anaerobic activity may disrupt gut microbial ecology, this study investigated their association with the risk of incident maculopathy. We conducted a nationwide population-based study using the National Health Insuranc…

Scientific Reports, Published online: 21 August 2026; doi:10.1038/s41598-026-67455-4 Refractive prediction errors of Barrett KCN, Kane KCN, SRK/T, and a customized approach in moderate-to-severe keratoconus after cataract surgery