dementia

The takeaway: Lewy body dementia accounts for up to 20% of dementia cases and is closely related to Parkinson’s disease due to the buildup of a protein in neurons in the brain. It can be difficult to diagnose, but new tests and approaches, combined with new drugs, are improving treatment and care. A neurologist recommends seeking help if you are having trouble with thinking and memory to identify…

Brain diseases, including dementia, have long been studied using experimental animals such as mice. However, differences between the human and animal genomes have raised concerns that some disease mechanisms may not be fully explained by conventional animal models.

A vaccine designed to prevent shingles may also be linked to a lower chance of dementia in older adults, according to a large U.S. study. Researchers found that people who received Shingrix after entering a skilled nursing facility were less likely to be diagnosed with dementia over the next four years. The study was led […] The post Could a Shingles Shot Help Protect the Brain from Dementia appe…

Hormone replacement therapy may be linked to a lower risk of dementia in some women after menopause, according to a large UK study. Researchers from the University of East Anglia and the University of Exeter found that the association was strongest in certain groups, including women who experienced surgical menopause. The findings suggest that the […] The post This Hormone Therapy May Lower Demen…

In a large Australian cohort of adults with hypertension, use of blood-brain barrier-crossing antihypertensive medications was associated with a lower risk of dementia and mortality than use of non-crossing drugs. The association was strongest for beta-blockers and angiotensin II receptor blockers, although the observational design means the findings cannot establish causality.

In a UK Biobank study of 183,450 postmenopausal women followed for an average of 13.3 years, hormone replacement therapy use was associated with a modestly lower risk of dementia, with stronger associations in women who had surgical menopause or shorter natural estrogen exposure. The relationship also varied by age at HRT initiation, while the observational design means the findings cannot establ…

In people diagnosed with early-onset Alzheimer's disease, a biomarker tool that detects shrinkage of the brain's gray matter may predict how quickly someone may progress from mild cognitive impairment (MCI) to dementia, according to a new study published August 26, 2026, in Neurology(r), an official journal of the American Academy of Neurology.

Peer-reviewed research provides proof of concept that an app based on the DICE approach can improve outcomes for caregivers and people living with dementia.

Jaw-dropping patient videos and miraculous testimonials ignited a frenzy in China over a technique that aims to improve drainage from the brain in dementia patients. Now it is entering trials worldwide

Could estrogen use in older women be connected with a healthier brain? A study of more than 21,000 women found that those who had used estrogen-only hormone therapy later in life had fewer signs of Alzheimer’s disease and were less likely to be diagnosed with dementia. The result is intriguing, but researchers say it should […] The post Estrogen Therapy May Lower Dementia Risk in Women appeared f…

Alzheimer’s is the most common form of dementia. Here’s why knowing about the diversity of dementia matters.

BackgroundWhether a person with dementia receives a specific subtype diagnosis rather than a nonspecific label is a marker of diagnostic completeness. Subtype shapes safe management, including psychotropic prescribing, behavioural and psychological symptom management, and eligibility for Alzheimer’s disease therapies, yet nonspecific labels remain common where specialist assessment is unevenly ac…

ObjectivesAlthough MRI is the optimal imaging method for assessing white matter hyperintensity (WMH), it lacks sensitivity to the underlying pathophysiological changes of WMH. This study aims to investigate EEG changes associated with WMH and identify potential EEG biomarkers for WMH-related dementia.MethodsThis cross-sectional study enrolled 90 subjects: 30 patients with WMH with dementia (WMHD)…

Dementia is usually noticed when a person begins forgetting names, repeating questions, getting lost, or struggling with everyday tasks. However, scientists now know that the disease starts developing many years before these symptoms appear. Changes inside the brain can begin 10, 20, or even 30 years before memory problems become obvious. This means there may […] The post Simple Blood Test May Pr…