toxicology

[Redox Report] The authors investigated the molecular mechanisms underlying oxidative damage to the intestinal barrier and intestinal epithelial cell toxicity by the natural co-occuring pollutants, Cr(VI) and DON, using the network toxicology method and cell intervention experiments.

DNP, found to be in the supplements, is commonly used as a pesticide, the U.S. Food and Drug Administration warns.

Chemical hair-straightening products are widely used and often assumed to be harmless. However, growing clinical evidence suggests that certain formulations may cause severe nephrotoxicity through systemic absorption of glyoxylic acid or related compounds.

Scientific Reports, Published online: 02 September 2026; doi:10.1038/s41598-026-69231-w Retraction Note: Melatonin loaded poly(lactic-co-glycolic acid) (PLGA) nanoparticles reduce inflammation, inhibit apoptosis and protect rat’s liver from the hazardous effects of CCL4

Mould toxins (mycotoxins) in food are not rendered harmless by the heat generated during baking or cooking and may therefore retain their harmful properties. Many consumers are unaware of this fact, as shown by a recent survey conducted by the German Federal Institute for Risk Assessment (BfR). “As ...

Scientific Reports, Published online: 29 August 2026; doi:10.1038/s41598-026-39077-3 Asbestos mineral fibre exposure significantly affects volatile organic compound profiles of mesothelial cell lines in vitro

A popular vanilla flavoring in e-cigarettes may interfere with some of the earliest steps of human development. In lab experiments, vanillin caused embryonic stem cells to lose their ability to develop normally and pushed them toward forming only certain types of tissue.

ObjectivePer- and polyfluoroalkyl substances (PFAS) are omnipresent, persistent contaminants associated with rising ovarian cancer incidence; however, the molecular circuitry linking PFAS to ovarian tumorigenesis remains obscure.MethodsHere, an integrated network toxicology–molecular docking pipeline was developed to interrogate ten environmentally abundant PFAS.ResultsComprehensive interactome m…

A study in mice found that a protein called saxiphilin acts like a sponge against a deadly toxin produced by algal blooms. The harmful agent, which accumulates in certain seafood, can cause a life-threatening illness called paralytic shellfish poisoning

IntroductionFragrance products are widely used in daily life. Nevertheless, the biological effects associated with specific fragrance formulations remain insufficiently characterized due to the complexity of their chemical composition. This study aimed to provide an integrated multi-organ evaluation of the effects of inhaling a tested commercial fragrance formulation on oxidative stress, physiolo…

Zebrafish have become one of toxicology's most powerful tools for studying emerging contaminants, from PFAS and microplastics to pharmaceuticals and nanomaterials.

This study examined the interaction between Fusarium solani KMZW-1 and adult Bactrocera dorsalis, with emphasis on cuticular colonization, adult-stage pathological effects, and candidate metabolite-mediated toxicity. KMZW-1 showed Fusarium-like colony and conidial morphology and colonized mainly tarsal setae, joints, and recessed cuticular regions, where fungal conidia and hyphae progressively ac…