Diagnostics Daily News

Diagnostics World | Epigenetic methylation markers on your DNA can be used to predict your biological age, how soon you’ll die, or the development of various age-related diseases and morbidities. Researchers at the University of Southern California have extended these tests by looking at all of the gene transcription taking place as a function of each of five different popular clock predictors, i…

Diagnostics World | Artificial intelligence can help reengineer pathology toward the point of care and provide guidance to first-on-the-scene responders, including those in military battlefields with no internet connectivity and limited medical training. The technological possibilities are driven largely by the data foundation that AI models learn from and analyze as well as institutions finding …

Diagnostics World | For decades now, doctors have been referring people suspected of having obstructive sleep apnea to a specialized medical facility for a polysomnogram (PSG). The gold-standard overnight test collects millions of data points from across the body, only a small subset of which gets prioritized for scoring the severity of the condition—notably, the apnea-hypopnea index (AHI) rankin…

Diagnostics World | Researchers at The University of Texas MD Anderson Cancer Center are investigating whether immune-system biomarkers could help identify cancer patients most likely to benefit from rapid-acting psychedelic treatments for depression. Researchers examined whether these rapid-acting antidepressants share biological pathways that could serve as biomarkers for future treatment strat…

Diagnostics World | Analyzing genetic changes in cancer cells provides insight into how tumors develop and help with developing treatment through precision oncology. Long-read sequencing can help, but there is still a higher error rate compared to short-read sequencing. Researchers at The University of Hong Kong addressed this gap with ClairS, a tool designed to identify small cancer-related gene…

Diagnostics World | The worried well the world over now have readily accessible and easy to self-administer home tests for assessing their risk for diabetes and chronic kidney disease, thanks to the computational skills of a pair of researchers at DTU Sustain, based at the Technical University of Denmark. The new online tools focus on a small number of parameters identified by artificial intellig…

Diagnostics World | Human Longevity last week announced the availability of Genomics for All, a clinical-grade whole genome sequencing product priced at $599. The offering sequences all 6.4 billion base pairs of an individual's DNA and delivers AI-interpreted results through the HLI app, with no clinic visit required.

Diagnostics World | PacBio made several announcements this week: Mark Van Oene is the new President and CEO for the company and new chemistry and software are available for its Vega systems. Both changes aim to position the company for wider platform adoption across labs and research areas.

Diagnostics World | Blood-based biomarkers predicting when symptoms of amyotrophic lateral sclerosis (ALS) will emerge are expected to catapult the medical research community forward in the quest to prevent the fatal neurodegenerative disorder. Researchers from the University of Miami Miller School of Medicine have been spearheading the Pre-Symptomatic Familial ALS (Pre-fALS) study collecting lon…

Diagnostics World | Indole-3-propionic acid (IPA) is increasingly recognized as a critical chemical shield and promising biomarker for gut inflammation. Levels of IPA are starkly deficient in the blood of patients with active ulcerative colitis (UC), but the gold standard measurement technique of liquid chromatography-mass spectrometry (LC-MS) is costly and requires highly trained technicians to …

Diagnostics World | Much like the trajectory of infectious disease diagnostics was changed by PCR and molecular methods, Epi One is looking to alter the course of cancer diagnostics with direct, highly sensitive molecular detection of specific epigenetic biomarkers of multiple malignancies. First out of the gate will be a prostate cancer re-biopsy decision tissue-based assay, immediately followed…

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