pain-management

Knee osteoarthritis is one of the most common causes of pain and disability around the world. The condition develops when the tissues inside the knee joint gradually wear down over time. As the disease progresses, people often experience pain, stiffness, swelling, and difficulty walking, climbing stairs, or taking part in activities they once enjoyed. According […] The post New Nonsurgical Treatm…

Pain affects over 30% of the global population, with an underlying pathogenesis involving a complex interplay of biopsychosocial factors. Despite the availability of conventional pharmacological and interventional therapies, their clinical utility is frequently constrained by concerns regarding substance misuse, surgical complications, and other adverse sequelae. Acoustic stimulation (AS) has eme…

The takeaway: A CU Anschutz-led review examined whether spinal cord stimulation can help manage chronic pain in people with spinal cord injuries. Researchers found only 10 eligible studies involving 43 patients, but many participants reported substantial reductions in pain, along with improvements in sleep and quality of life. Because the available evidence is limited and based largely on small c…

SSRI affiliate has secured major federal funding to study why sickle cell disease patients experience pain so differently, and what that means for their care. […] The post New $5.1 Million Grant Will Help Doctors Better Understand and Treat Sickle Cell Pain appeared first on Duke Social Science Research Institute .

Embolization of abnormal blood vessels using rapidly resorbable gelatin-based microspheres is safe and provides significant, lasting pain relief and functional improvement for patients with osteoarthritis-related knee pain, according to a new study published today in Radiology, a journal of the Radiological Society of North America (RSNA).

Patients who had a nerve block experienced good pain control during procedure, but some sought follow-up care for ongoing pain. The post Study sheds light on managing pain in wrist fracture surgery appeared first on Kaiser Permanente Division of Research .

4E Therapeutics, Inc. ("4E"), an Austin-based neuroscience company developing next-generation treatments for chronic pain, today announced that it has been acquired by Eli Lilly and Company ("Lilly").

IntroductionThe treatment of neuropathic pain with traditional and adjuvant analgesics is limited in efficacy and associated with severe adverse effects. Our group has previously shown that somatostatin, released from capsaicin-sensitive peptidergic sensory nerve terminals, mediates analgesic and anti-inflammatory effects at the peripheral and central levels via the somatostatin receptor subtype …

Purpose of Review Intervention trials for cervicogenic headache (CGH) often yield equivocal results with marked treatment effect heterogeneity, possibly reflecting variations in underlying pain mechanisms throughout the CGH population. Pain phenotyping or classifying patients into subgroups based on their predominant pain mechanism may facilitate more precise CGH treatment. This review aims to ex…

A drug strategy abandoned after causing tremors, seizures and death in animals has been revived with a redesign that makes the compound less “sticky” — allowing it to let go faster from its target in the spinal cord. In mice, the new version relieved neuropathic pain without the dangerous side effects that derailed earlier attempts, potentially opening a new path beyond opioids for chronic nerve …

A drug strategy abandoned after causing tremors, seizures and death in animals has been revived with a redesign that makes the compound less “sticky” — allowing it to let go faster from its target in the spinal cord. In mice, the new version relieved neuropathic pain without the dangerous side effects that derailed earlier attempts, potentially opening a new path beyond opioids for chronic nerve …

For millions of people living with osteoarthritis, daily life can involve a frustrating cycle of pain and stiffness. While current treatments like over-the-counter medications or steroid injections can temporarily dull the ache, they do not stop the joint from deteriorating.

Scientific Reports, Published online: 09 June 2026; doi:10.1038/s41598-026-56099-z Correction: Effects of DRG pulsed radiofrequency parameters on the clinical outcome for battered sensory never syndrome: a prospective, triple-blind, randomized controlled trial

BackgroundLiposomal bupivacaine (LB) provides prolonged postoperative analgesia. This study aimed to evaluate the analgesic efficacy of erector spinae plane block (ESPB) using LB in patients undergoing spinal surgery.MethodsA total of 64 patients undergoing elective spinal surgery were randomly assigned in a 1:1 ratio to receive ESPB with 0.44% liposomal bupivacaine (LB group) or 0.4% ropivacaine…

A new study suggests that lingering rheumatoid arthritis symptoms are not always caused by ongoing inflammation. For people with rheumatoid arthritis, lingering pain and fatigue are often assumed to be signs that inflammation remains active. But new research suggests the real culprit may sometimes lie elsewhere. Researchers at Semmelweis University report that sleep disorders, depression, [...]

Back pain is one of the most common health problems in the world. Nearly everyone experiences it at some point in life. For some people, back pain appears after lifting a heavy object, bending awkwardly, or spending too much time sitting. In many cases, the pain improves within a few days or weeks. However, for […] The post New Injection Treatment May Help Ease Chronic Back Pain appeared first on…

For people living with osteoarthritis, everyday activities such as walking, climbing stairs, or getting out of a chair can become increasingly difficult. The disease affects hundreds of millions of people worldwide and is one of the leading causes of disability among older adults. Although doctors have many ways to manage pain, there is still no […] The post Existing Drug May Repair Joint Damage …

Scientific Reports, Published online: 30 May 2026; doi:10.1038/s41598-026-52127-0 Comparing the effects of ischemic compression and kinesiology taping techniques in patients with chronic low back pain

‘Tennis became a race against time’ after 2005 diagnosis ‘The suffering was less than my passion,’ says tennis great Rafael Nadal has revealed he spent most of his career in pain as he willed himself to play through a chronic foot injury and went on to win 22 grand slam titles while spending two decades ruling men’s tennis alongside Roger Federer and Novak Djokovic. The Spaniard, who retired in 2…