GEN – Genetic Engineering and Biotechnology News

For nearly a decade, the Beacon platform has advanced from integrated single-cell cloning to earlier productivity, product-quality, and stability measurements, with AI-assisted clone evaluation pointing toward the next step. Bringing richer evidence forward helps teams focus resources on the candidates most likely to succeed. The post Measuring Cell Line Development Quality Within Days of Single-…

The expanded next-generation sequencing offering from Clean Cells now covers GMP-compliant viral safety testing for viral vectors and recombinant preparations, building on existing identity testing capabilities. The post Clean Cells Broadens Viral Safety Testing Portfolio with NGS appeared first on GEN - Genetic Engineering and Biotechnology News .

New financing will help Moonwalk Biosciences expand its pipeline of siRNA medicines targeting adipose tissue while building out its proprietary drug discovery platform. The post Moonwalk to Use $70 Million to Develop RNAi Therapies for Obesity, Cardiometabolic Disease appeared first on GEN - Genetic Engineering and Biotechnology News .

This eBook brings together expert perspectives on several of the most pressing analytical topics facing today’s cell and gene therapy developers. The post The Analytical Blueprint for Cell & Gene Therapy Success appeared first on GEN - Genetic Engineering and Biotechnology News .

The companies that emerge from this evolving regulatory cycle with clean, rigorous, globally positioned programs will find themselves in a structurally superior competitive position when the environment stabilizes. The post Navigating the Regulatory Labyrinth: How Biotech Leaders Are Rethinking Strategy in an Uncertain Regulatory Era appeared first on GEN - Genetic Engineering and Biotechnology N…

Loss of function in the ALDH3B2 gene can convert human pancreatic duct cells into functional β-like cells that in tests secreted insulin in response to glucose, and lowered blood glucose levels when transplanted into diabetic mice. The post Human Pancreatic Duct Cells Show Diabetes Therapy Potential appeared first on GEN - Genetic Engineering and Biotechnology News .

Single-use systems (SUS) bioprocessing technology has become mainstream. But the more interesting question today is what the industry needs next, and how SUS will enable the future. The post Single-Use Comes of Age–What Comes Next? appeared first on GEN - Genetic Engineering and Biotechnology News .

New research identifies long-lived lung immune cells that support protective T-cell memory, suggesting galectin-1 could enhance flu vaccines and improve respiratory immunity against influenza infection. The post Key Immune Cells Identified That Could Strengthen Flu Vaccines appeared first on GEN - Genetic Engineering and Biotechnology News .

By targeting specific neuron types in the Drosophila brain, researchers linked distinct octopamine/tyramine cell types to behaviors including aggression suppression and visual motion tracking. The post Genetic Toolkit Isolates Neuron Types in <i>Drosophila</i> Brain appeared first on GEN - Genetic Engineering and Biotechnology News .

Study showed nearly all mothers had detectable organophosphate pesticide levels in urine during pregnancy, yet team found no significant relationship in children between this exposure and traits related to autism. The post Multi-Academic Study Finds No Link Between Pesticide Exposure and Autism Traits appeared first on GEN - Genetic Engineering and Biotechnology News .

Scientists working their way back through millions of years of the evolutionary past of mammalian lactoferrin reconstructed extinct peptides, some of which in laboratory were more potent against drug-resistant bacteria than present-day counterparts. The post Ancient Peptides Resurrected from Lactoferrin’s Evolutionary Past Could Point to New Antibiotics appeared first on GEN - Genetic Engineering…

Kite Pharma has developed a flow virometry technique to analyze single lentiviral particles, which they hope will improve product consistency by characterizing viral vector size and surface features. The post New Cytometry Technique for Characterizing Viral Vectors appeared first on GEN - Genetic Engineering and Biotechnology News .

A new extracellular secretion system could help biopharmaceutical manufacturers bypass the problems that make traditional Escherichia coli-based recombinant endonuclease production a major challenge, according to the authors of a new study. The post Extracellular Secretion System Could Solve Industry Endonuclease Production Challenges appeared first on GEN - Genetic Engineering and Biotechnology …

A bioreactor designed to test biosensors that measure multiple parameters in real time is being developed as a simple, budget-friendly bioreactor for high schools and colleges to help prepare the biomanufacturing workforce of the future. The post Affordable Bioreactor Helps Prep Students for Biomanufacturing Careers appeared first on GEN - Genetic Engineering and Biotechnology News .

Steam sterilization has underpinned biomanufacturing for decades, but its infrastructure burden is increasingly difficult to ignore. Alternative technologies could reduce capital costs, accelerate plant construction, and help unlock industrial biotechnology capacity at much larger scales. The post Sterilization Posits Biomanufacturing Next Scaling Challenge appeared first on GEN - Genetic Enginee…

Pairing HER3-DXd with the PARP inhibitor olaparib increased DNA damage, induced apoptosis, and slowed tumor progression in vivo in preclinical non-small cell lung cancer models. The post PARP Inhibitor Combination Therapy Boosts Antitumor Activity in NSCLC Models appeared first on GEN - Genetic Engineering and Biotechnology News .

A study in mice found that male sex hormones can suppress allergic responses by promoting sympathetic nerve connections and norepinephrine release in the lungs. The post Male Sex Hormones Suppress Lung Allergies by Acting on Neurons in Mice appeared first on GEN - Genetic Engineering and Biotechnology News .

Researchers kept human brain organoids developing for over five years, revealing prolonged maturation that mirrors human brain development and creating new opportunities to study disorders and test drugs. The post Five-Year Brain Organoids Reveal New Insights Into Human Development appeared first on GEN - Genetic Engineering and Biotechnology News .

Researchers developed a computational tool that could help to finding genes most directly related to disease, and which in a reported study identified 21 genes related to asthma, most of which hadn’t been discovered by other methods. The post DANDELION Computational Tool Identifies Previously Unknown Asthma-Related Genes and Pathway appeared first on GEN - Genetic Engineering and Biotechnology Ne…

By using chemical signals to guide cells to adopt distinct regional identities, scientists created lab-grown human organoids that mimic early brain development and could illuminate how specialized brain areas emerge. The post Lab-Grown Neocortex Models Mimic Early Brain Organization appeared first on GEN - Genetic Engineering and Biotechnology News .