advanced-memory-and-neural-computing

A study of over 5,600 teenagers links video gaming to differences in brain structure, like a thinner cerebral cortex. However, these associations vary depending on whether adolescents engage in solo, social, or mature-rated gaming.

​Brain tumors do not grow in isolation. They develop within the highly active environment of the brain, where neurons continuously exchange electrical and chemical signals.

Virtual reality (VR) has gained traction in psychiatric research in exposure-based interventions for phobias, simulations of hallucinations in psychosis, and adaptations of cognitive-behavioral therapy. These applications demonstrate that emotionally immersive digital environments can meaningfully engage pathological processes in controlled settings. Yet VR’s potential in psychiatry goes beyond p…

Sleep is an essential biological function with unclear mechanisms. Recent research links the circadian clock, energy metabolism, calcium handling, reactive oxygen species (ROS) production, and synaptic plasticity to cognitive performance. Given that mitochondria regulate cellular energy production, calcium buffering, and ROS dynamics, it stands to reason that mitochondrial function plays a signif…

Clinically useful artificial intelligence and machine-learning studies in healthcare require interpretable features, internal validation, and explicit boundaries between primary inference and external context. Among 1,612 baseline Parkinson’s Progression Markers Initiative (PPMI) participants, 1,439 had evaluable post-baseline cognition and contributed 5,909 records through Year 5. Composite cogn…

The enteric nervous system (ENS), a central component of the gut-brain axis, is increasingly recognized as an important site in the pathogenesis of neurodegenerative diseases. In Parkinson’s disease (PD) in particular, gastrointestinal dysfunction and pathological changes within the ENS often precede symptoms in the central nervous system (CNS). According to the Braak hypothesis, disease-associat…

Although physical activity is consistently associated with lower risks of cognitive decline, dementia, and Parkinson’s disease, most exercise research in neurodegeneration still defines exposure by dose-based variables such as duration, intensity, frequency, step count, and cardiorespiratory fitness. This framework is useful for public-health guidance but biologically incomplete for progressive p…

Join our member, the Brain-Computer Interface Society, in Croatia for the 12th International BCI Meeting, the premier global gathering dedicated to brain–computer interface research and innovation. This landmark event will bring together scientists, engineers, clinicians, users, and industry leaders spanning all areas of BCI research, development, and clinical application. From cutting-edge basic…

Dementia and age-related memory problems are becoming an increasingly important health challenge as populations around the world grow older. Although people cannot change some risk factors, such as age or inherited genes, research suggests that everyday habits may influence how well the brain ages. Diet is one area receiving growing attention. Scientists have already studied […] The post Japanese…

Anxiety disorders are humanity's most common mental disorders, affecting some 359 million people globally. Controlled...

IntroductionThe reduction of α7 nicotinic acetylcholine receptor (nAChR) in the hippocampus con-stitutes one of the neuropathological features observed in the brains of individuals with Alzheimer’s disease (AD), and α7 nAChR is crucial to cognitive process. However, studies involving α7 nAChR knockout mice have not demonstrated any abnormal brain structure or damage to hippocampal neurons, a disc…

IntroductionGlutamate‐induced neurotoxicity is a shared pathological mechanism across neurodegenerative and neuropsychiatric disorders, but the mechanistic contributions of the sigma‐1 receptor remain unsolved and underappreciated.MethodsThis scoping review focuses on the pharmacological gaps in σ1R agonists by synthesizing mechanistic and bibliometric trends across the most influential literatur…

Called It! A single injection of a nanoparticle treatment engineered to encourage the generation of new brain cells was enough to reverse cognitive decline in an animal model of Alzheimer’s disease. Developed by researchers in the US, the remarkable new treatment could one day be used to treat patients in advanced stages of dementia by […]

ObjectiveTo investigate the effects of different motor skills (open and closed) on the cognitive switching function and hemodynamic response characteristics of the prefrontal cortex in male athletes, providing a neurocognitive basis for the scientific selection of high-level athletes and the development of personalized cross-training programs.MethodsThis study recruited a total of 31 male Level 2…

Placing too much emphasis on a specific interpretation of dimensionality, or treating it as an end-all quantification of some aspect of neural computation, may hinder progress in understanding the brain.